Usando o DNA de um fóssil, a cientista Catherine Vicily clona um temido animal: Tigre dente de Sabre. Ela não faz idéia da fúria que está prestes a desencadear ao mundo moderno. A ambição científica torna-se mortal, principalmente quando a criatura escapa e ataca sua presa - a raça humana. Agora, em uma caçada contra o tempo, o predador deve ser capturado antes que mais pessoas inocentes sejam brutalmente devoradas.
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