Fame and Phil, two popular sibling YouTubers, check in to Srichanphen Hotel for a state-mandated fourteen-day quarantine during the height of the pandemic. Also in Fame’s and Phil’s group are Leo, a quiet young man who arrives with his sister Lena and their father, and Steve, an ill-tempered American. In the hotel, they encounter strange events.
Centipedes crawl out from every nook and cranny to attack the group, and then Fame and Leo find a mysterious corpse in a fire escape. Later they discover that a monster is lurking in the hotel: a giant centipede that resides in the human body as a way to prolong its existence. The centipede possesses the body of a person, assumes the human shape and personality, and then seeks out its next host, on and on. So it’s impossible to tell if any of the hotel guests is actually the monster in disguise.
The giant centipede finds out that Fame has a special blood type that enables it to extend its life forever, and Fame suddenly becomes its prime target. Leo has to find a way to save Fame along with his father and sister by seeking a safe route out of the hotel now surrounded by the deadly army of centipedes…