Natasha e alguns amigos resolvem entrar na Amazônia a fim de participarem da cerimônia do Santo Daime numa aldeia da região. Eles contratam o experiente Beto Careca para guiá-los, mas em seu lugar aparece Jean Pierre. No caminho, estranhos assassinatos ocorrem na região, cada vez mais perto dos amigos, ameaçando a segurança do grupo. O que eles não sabem é que no interior da floresta vive o dr. Moreau, médico nazista que realiza escondido experimentos bizarros.
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