Quando Jane Browning fica exposta a uma arma biológica que altera seus genes, ela ganha poderes de se auto-curar e habilidades físicas e mentais. Agora, fugindo de uma organização sinistra determinada a replicar seus poderes - ou destruí-los - Jane junta forças com alguns improváveis aliados para se tornar uma agente secreta na luta contra o crime.
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/media/movies/covers/2009/10/7daf5370e887c4898de57ab105c97a00.jpg "Painkiller Jane: Poster Oficial")
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