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Barsarato é uma ilha no Caribe, onde a doutora Linda Flemming (Melody Thomas Scott) e seu filho de 18 anos William (Gregory Wooddell) passam férias. Assim que são recepcionados, vêem que um dos habitantes da ilha desmaia na frente do jipe e tem reações estranhas. Linda, especialista em doenças infecciosas, percebe que a pessoa tem lesões virais contagiosas e suspeita que o vírus possa ser disseminado rapidamente. Mas uma médica local explica que os primitivos da ilha não acreditam na medicina ocidental.
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