Um grupo de amigos parte para uma pequena cidade do interior da Inglaterra com o objetivo de deixarem para trás os respectivos desgostos amorosos de cada um. Sendo que neste lugar existem quatro mulheres por cada homem, tudo parecia indicar que este ia ser o melhor fim de semana de todos, mas o que ninguém previa era que a população desta cidade tivesse sido contaminada por um vírus que transforma as mulheres (e apenas as mulheres) em terríveis criaturas canibais e psicóticas.
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