Depois de testemunhar a doença e a pobreza nos bairros miseráveis de Nova Iorque, a imigrante italiana Francesca Cabrini embarca em uma ousada viagem para persuadir o hostil presidente da câmara a fornecer alojamento e cuidados de saúde a centenas de crianças órfãs.
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Críticas e opiniões sobre Cabrini