No longa, a talentosa pianista Nina (Giulia Be) precisa superar os desafios de lidar com o lúpus, uma doença autoimune que pode atacar qualquer parte do corpo - o rim, no caso dela. A jovem é surpreendida por uma forte conexão com Gabriel (Henry Zaga), um dos médicos da equipe que a atende, que irá ajudá-la a superar suas inseguranças na luta para tocar nos palcos junto a uma grande orquestra de São Paulo.
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