Bruno Salvati leva uma vida insatisfatória: é um cineasta (com pouco sucesso) e acaba de se separar de sua esposa Anna, mãe de seus dois filhos adolescentes. Um dia, Bruno descobre que sofre de uma doença e precisa de um doador. A revelação de seu estado de saúde leva o cineasta a reavaliar os laços familiares, principalmente com o pai Umberto. Será o pai quem vai revelar um segredo que vai levar o filho a viajar em busca de alguém que o possa ajudar.
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