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Filha do cantor e compositor Nando Reis, Sophia estreou no cinema representando a personagem Isa, em Meu Tio Matou um Cara. Estudou alguns anos na Casa do Teatro, em São Paulo. Em março de 2008, foi contratada para ser VJ da MTV Brasil, onde permaneceu durante 2 anos, apresentando em 2008 o programa Top 10 aos sábados, e em 2009, o programa Acesso MTV, ao lado de Léo Madeira e Kika Martinez. Abandonou a emissora no início de 2010. Em 2011 passou a fazer parte do programa A Liga, exibido pela Band, substituindo Rosanne Mulholland. Atualmente, apresenta o “Eu Nunca” na TV Gazeta, onde leva famosos e anônimos para fazerem coisas que nunca fizeram antes.
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