O filme Mostra a trajetória de dois médicos que inventaram a cirurgia com implantes de silicone para os seios. Em 1962, o então médico residente Kevin Saunders (David Schwimmer) começa a pensar no assunto e procura o doutor William Larson (Chris Cooper). Os dois criam o que viria a ser o primeiro procedimento cirúrgico neste sentido, mas, para colocá-lo em prática, precisam de voluntárias. A primeira ideia - procurar por elas nas ruas - fracassa e eles passam a colocar anúncios nos jornais. A ideia começa a dar certo, mas a fama e o dinheiro vai levar estes dois médicos por caminhos bem diferentes...
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