Jane Marks (Brenda Blethyn) é a vaidosa e iludida mãe de três mulheres de personalidades diferentes: a mais velha, Michelle (Catherine Keener) é uma mulher perdida, irônica e amarga; Elizabeth (Emily Mortimer) é uma atriz sem auto-estima; e a filha adotiva Annie (Raven Goodwin) é obesa e arrogante.
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/media/movies/covers/2010/10/a7bfc5701664fac7cfe228d54e0c6060.jpg "Poster 1 de Filme Encontro de Irmãs (2001)")
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/media/movies/covers/2010/10/a7bfc5701664fac7cfe228d54e0c6060.jpg "Encontro de Irmãs: Poster Oficial")
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