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David Krumholtz, é um ator americano mais conhecido por interpretar o Professor Charlie Eppes na série de televisão ''Numb3rs''.
Krumholtz nasceu em Queens, Nova York. Ele é o filho de Judy, uma assistente de dentista, e Krumholtz Michael, um trabalhador postal. Ele cresceu em uma "classe trabalhadora, quase pobre" e é de uma família judaica. Sua mãe se mudou de Hungria para os EUA em 1956, e seus avós paternos emigraram da Polônia.
Krumholtz começou sua carreira de ator com 13 anos, quando ele seguiu seus amigos para um teste aberto para a peça da Broadway My Father (1992). Embora ele não esperasse conseguir o papel, ele ganhou o papel de Charlie Young antagonista de Judd Hirsch, com Tony Shalhoub e Jason Biggs, que também estava fazendo sua estreia na Broadway. Logo após a sua corrida na Broadway, Krumholtz co-estrelou em dois filmes, a vida com Mikey (1993), contracenando com Michael J. Fox, e Família Addams (1993) antagonista de Christina Ricci. Por seu papel em Mikey, David foi nomeado para um jovem Artist Award em 1993. Embora o seu trabalho nesses dois filmes lhe rendeu a atenção da crítica, David é provavelmente mais conhecida pelas crianças como o sarcástico elfo Bernard de The Santa Clause (1994) e The Santa Clause 2: a cláusula senhora(2002), mas devido a sobreposição com as filmagens Numb3rs (2005) foi incapaz de participar de The Santa Clause 3: O escape Clause.
Em 2007, ele vai morar em Los Angeles, onde Numb3rs foi produzido.
Em 22 de maio de 2010, Krumholtz casa com a atriz Vanessa Britting no Hotel Plaza em Nova York. O casal estava junto desde julho de 2008.
Em setembro de 2011, Krumholtz foi diagnosticado com câncer de tireoide, em dezembro do mesmo ano começa um tratamento com iodo radioativo.
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