Jane Marks (Brenda Blethyn) é a vaidosa e iludida mãe de três mulheres de personalidades diferentes: a mais velha, Michelle (Catherine Keener) é uma mulher perdida, irônica e amarga; Elizabeth (Emily Mortimer) é uma atriz sem auto-estima; e a filha adotiva Annie (Raven Goodwin) é obesa e arrogante.
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