Dois jovens, Jack e Pilot (Jared Leto e Jake Gyllenhaal), decidem fugir de Las Vegas para Seattle para escapar de gângsteres. No caminho conhecem várias pessoas, incluindo a prostituta Cassie (Selma Blair) e um quarto passageiro que está indo para Seattle por causa da morte de Kurt Cobain, ex-vocalista da banda Nirvana. Eventualmente Jack começa a suspeitar das razões de Pilot ter escolhido Seattle como o seu destino.
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/media/movies/covers/2011/10/75ea73421649c0e1c26c8878fd74dc98.jpg "Poster 1 de Filme Fuga Desenfreada (2002)")
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